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It concerns the special treatment accorded to children with Down's Syndrome (once called 'Mongolism') in just one pediatric cardiology clinic. Infection of endothelial cells (EC) with Rickettsia rickettsii results in Rocky Mountain spotted fever, an acute illness characterized by systemic inflammation. An a... Qualitative sociology too easily succumbs to a ‘Romantic’ impulse. Presentations on veterinary rickettsiology highlight the importance of the rickettsiae in animal husbandry. Rickettsia rickettsii-induced Apoptosis in NF-κB-blocked Human Endothelial Cells Involves Activation of Caspase-3. This book assembles a team of internationally-renowned researchers who share a commitment to rigorous, analytically-derived but non-polarized, qualitative research. Such work can lack analytic rigour, failing to distinguish the sociologist from the journalist. Taking theory too far? A 1.8-fold increase in secreted PAI-1 activity occurred in infected versus control cultures (p = 0.03) at 24 h but not at earlier timepoints. Adhesion, entry, intracellular growth, and host cell responses, Western blotting analysis of heat shock proteins of Rickettsiales and other eubacteria, Rickettsia Rickettsii Infection of the Ea.Hy 926 Endothelial Cell Line: Morphological Response To Infection and Evidence for Oxidative Injury, Proteasome-Independent Activation of Nuclear Factor κB in Cytoplasmic Extracts from Human Endothelial Cells byRickettsia rickettsii, Effects of the antioxidant alpha-lipoic acid on human umbilical vein endothelial cells infected with Rickettsia rickettsii, NF-kappa B-dependent Inhibition of Apoptosis is Essential for Host Cell Survival during Rickettsia rickettsii Infection, NF-KB-dependent inhibition of apoptosis is essential for host cell survival during Rickettsia rickettsii infection, Transcriptional Regulation of Endothelial Cell Tissue Factor Expression during Rickettsia rickettsiiInfection: Involvement of the Transcription Factor NF-κB, Superoxide Dismutase-Dependent, Catalase-Sensitive Peroxides in Human Endothelial Cells Infected by Rickettsia rickettsii, Rickettsia rickettsii infection of cultured human endothelial cells induces NF-KPB activation, Increased Expression of Plasminogen Activator Inhibitor-1 in R.rickettssi-infected Endothelial Cells, Hyperthermia increases ICAM-1 expression and lymphocyte adhesion to endothelial cells, Rickettsia rickettsii has proteins with cross-reacting epitopes to eukaryotic phospholipase A2 and phospholipase C, Infection of human endothelial cells by Rickettsia rickettsii causes a significant reduction in the levels of key enzymes involved in protection against oxidative injury, Rikettsia Rickettsii infection of cultured human endothelial cells induces tissue factor expression, Rickettsia rickettsii infection of cultured human endothelial cells induces tissue factor expression, E-Selectin-Dependent Neutrophil Adhesion to Rickettsia rickettsii-Infected Endothelial Cells, E-selectin-dependent neutrophil adhesion to Rickettsia rickettsii- infected endothelial cells, Rickettsia rickettsii induces superoxide radical and superoxide dismutase in human endothelial cells, Penetration of host cells by Rickettsia rickettsii appears to be mediated by a phospholipase of Rickettsial origin, Heparin protects human endothelial cells infected by Rickettsia rickettsii, Rickettsia rickettsii infection of cultured endothelial cells induces release of large von Willebrand factor multimers from Weibel-Palade bodies, Some contributions of electron microscopy to the study of rickettsiae, A Potential Protective Role for Thiols against Cell Injury Caused by Rickettsia rickettsii, Experimental infection of human vascular endothelial cells by pathogenic and nonpathogenic hantaviruses, Production of antibody to and cellular localization of erythrocyte-sensitizing substance from Rickettsia rickettsii, Potential for free radical-induced lipid peroxidation as a cause of endothelial cell injury in Rocky Mountain spotted fever, Infection and injury of human endothelial cells by Rickettsia rickettsii, Adherence of Platelets to Human Endothelial Cells Infected by Rickettsia rickettsii, Rickettsia rickettsii-induced cellular injury of human vascular endothelium in vitro, Infection of Human Vascular Endothelial Cells by Rickettsia rickettsii, Penicillin-Induced Unstable Intracellular Formation of Spheroplasts by Rickettsiae, Some characteristics of heavy and light bands of Rickettsia prowazekii on Renografin gradients, In Vitro Studies of Rickettsia-Host Cell Interactions: Ultrastructural Study of Rickettsia prowazekii-Infected Chicken Embryo Fibroblasts, In vitro studies of rickettsia-host cell interactions: Ultrastructural changes induced by Rickettsia rickettsii infection of chicken embryo fibroblasts, Simple, differential staining technique for enumerating rickettsiae in yolk sac, tissue culture extracts, or purified suspensions, Model for DNA packaging into bacteriophage T4 heads, External layers of Rickettsia prowazekii and Rickettsia rickettsii: Occurrence of a slime layer, Comparative ultrastructural study on the cell envelopes of Rickettsia prowazekii, Rickettsia rickettsii, and Rickettsia tsutsugamushi, In vitro studies on Rickettsia host cell interactions: lag phase in intracellular growth cycle as a function of stage of growth of infecting Rickettsia prowazeki, with preliminary observations on inhibition of rickettsial uptake by host cell fragments, Dengue virus induced modifications of host cell membranes, Modification of antityphus antibodies on passage through the gut of the human body louse with discussion of some epidemiologic and evolutionary implications, Interaction of the 5′-ends of 28S RNA in dimerization of hamster ribosomes, Ultrastructural Studies of Rickettsia prowazeki From Louse Midgut Cells to Feces: Search For “Dormant” Forms, Reversion of Ribosomal Helix Formation in Escherichia coli, Expression of Differentiated Functions in Mouse Neuroblastoma mediated by Dibutyryl-cyclic Adenosine Monophosphate, Ribosomal Helices: Formation in Escherichia coli During Acidic Growth, Infection ofHumanEndothelial Cells byRickettsia rickettsii Causes aSignificant Reduction intheLevels ofKeyEnzymes Involved inProtection against Oxidative Injury, SomeCharacteristics ofHeavyandLight BandsofRickettsia prowazekii onRenografin Gradients, Interference with the Folin reaction by penicillin and some of its semisynthetic derivatives, Department of Clinical and Experimental Medicine. Although laboratory mice are susceptible to Ehrlichia infections, many isolates do not cause clinical illness. His latest book is Thundersticks: Firearms and the Violent(2016). Microscopic examination of tissues at 48 and 96 h post-infection revealed characteristic pathologic featu... Rickettsia rickettsii, a gram-negative and obligate intracellular bacterium, is the causative agent of Rocky Mountain spotted fever. Based on antigenic, genetic, growth, and epidemiological characteristics, the genus is divided into the typhus group, which includes two human pathogens, Rickettsia prowazekii and R. typhi, and R. canada, which is kn... Heat shock proteins (Hsp) of four Rickettsia species, three Bartonella species, two Ehrlichia species, Orientia tsutsugamushi and seventeen other eubacterial species were characterized by the enhanced chemiluminescence Western blotting (WB) technique with antibodies raised against recombinant Hsp from Escherichia coli and purified GroES from R. typ... 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